Proliv Rx
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A new path forward for Veterans living
with depression.

FDA-ApprovedClinically ProvenPhysician-Directed

If you’re struggling with depression that hasn’t improved with medication alone, Proliv®Rx offers a new path forward.

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Veteran using Proliv Rx
Proliv Rx for Veterans

Why Proliv®Rx?

Depression therapy
from the comfort of your home

Many Veterans experience symptoms of depression as a result of the unique physical and emotional challenges associated with military service. Accessing specialized care can be difficult, particularly when travel, scheduling, or distance create barriers to treatment. For those who have not achieved adequate relief from antidepressant medications, finding the next treatment option can add another layer of complexity. Proliv®Rx offers a different approach – enabling eligible patients to receive therapy from the comfort of home while remaining connected to their healthcare providers and care team throughout treatment.

Does it work?

In the Proliv®Rx clinical study, 87% of patients with prior inadequate response to antidepressant medications improved by one or more depression severity levels; 56% reached mild or no depression, and 31.7% achieved full remission.

Strong Therapeutic Effect Evident by Week 16

87%
Of patients experienced substantial improvement in depression severity level.
After 16-week therapy program
~1 in 3
Patients achieved full remission.
After 16-week therapy program

How it works

Your brain is a network of more than 80 billion neurons that communicate using tiny electrical signals. These signals share information across different regions of the brain.

In depression, communication between regions becomes disrupted, affecting mood and emotional well-being.

Proliv®Rx is designed to improve communication and connectivity across the brain. Using advanced neuromodulation, it harnesses the brain’s natural capacity to change, helping build healthier neural connections.

With its wearable headset called the NeuroRouter, Proliv®Rx delivers gentle electrical signals through electrodes (NeuroPorts) placed on the forehead and the back of the head.

Much like how a router directs signals in a network, the NeuroRouter helps guide these signals precisely and non-invasively along natural nerve pathways to key regions involved in depression.

With consistent use, Proliv®Rx may helps restore balance in your brain, so you can feel better again.

Is it safe?

  • Proliv®Rx is FDA-approved and met the highest FDA requirements for safety.
  • As a non-invasive therapy, Proliv®Rx has generally mild to moderate side effects.
  • Throughout the therapy, data-driven reports may be shared with your prescribing physician, supporting ongoing monitoring progress and treatment plan adjustments when needed.

Fits into your daily routine

Portable and travel-friendly, Proliv®Rx is designed to fit seamlessly into daily routines, helping patients maintain treatment continuity wherever they are.
The therapy is administered at home through two 40-minute sessions per day over a structured 16-week treatment program.

Explore Additional Information On Clinical Evidence And Safety
Clinical Evidence and Safety
Quick self-check

Is Proliv®Rx right for you?

*Your physician will assess other factors to determine if Proliv®Rx is right for you.

Age 22 or older
Diagnosed with major depressive disorder
Tried at least one antidepressant without sufficient improvement
Ready to commit to the structured therapy program
Access to a smartphone for your two daily treatment sessions
Sounds like you?

Take the next step – Complete a short form and a care specialist will help you understand your options

Get Proliv®Rx – Request information

We’re here to help you take the next step

Understanding treatment options and navigating the VA healthcare system can feel overwhelming. By completing this short form, you’ll receive information about Proliv®Rx and can connect with someone who can help you better understand potential access pathways and next steps.

Consent & Privacy Notice – By submitting this form:
  • I agree that Neurolief may collect and use the information I provide in this form to contact me regarding Proliv®Rx, provide educational materials, answer my questions, discuss access options, and connect me with appropriate resources.
  • I understand that submitting this form does not create a patient-provider relationship and does not guarantee eligibility for, coverage of, or access to Proliv®Rx.
  • I understand that my information may be used by Neurolief and its authorized service providers for customer support, educational communications, and other business purposes consistent with applicable privacy laws and Neurolief’s Privacy Policy.